Keyed caps for containers and devices and systems related thereto

ABSTRACT

In some aspects, a keyed cap for a container is provided. Furthermore, in some aspects, a keyed container device including a container and the keyed cap for the container is also provided. Still further, in some aspects, a keyed containing system including a container, keyed cap for the container, and an electronic device having a keying element that is adapted to mate or otherwise fit with a specific keying element on the keyed cap. If a keyed cap has a keying element that does not correctly correspond to a specific keying element on an electronic device, then the keyed cap will not properly mate with the keying element on the electronic device. For example, the two keying elements that do not match may not fit sufficiently far enough within each other to permit the piercing member on the electronic device to reach a septum on the cap.

CROSS-REFERENCE

This application claims the benefit of U.S. Provisional PatentApplication No. 61/780,355 filed Mar. 13, 2013, which application isincorporated herein by reference in its entirety.

INTRODUCTION

Containers containing reagents are often loaded into loading ports ofelectronic devices to perform various testing, analysis, processing,etc., with the reagents. When loaded into the ports, a needle orpiercing member is used to pierce the cap of the container to withdrawfluid for testing. Inserting containers with specific reagents into thewrong loading port, however, may lead to wasting of reagent, as well aspotential cross-contamination. If cross-contamination occurs, additionalsteps may be required, such as flushing or otherwise decontaminating thesystem, which leads to wasted time and inconvenience for the user.

SUMMARY

In some aspects of the present disclosure, a keyed cap is provided. Thecap includes a cap body and a septum disposed in the cap body. The capbody has a first side and a second side. The first side of the cap bodyis opposite the second side of the cap body. The septum has a first sideand a second side. The first side of the septum is opposite the secondside of the septum. Further, the first and second side of the septumfaces a same direction as the first and second side of the cap body,respectively. The first side of the cap body includes a first side ofthe septum and a coupling element for coupling to a container. Thesecond side of the cap body includes the second side of the septum and akeying element. The keying element includes at least one annular ringthat protrudes from the second side of the cap body and that is disposedconcentrically around the septum.

In some aspects of the present disclosure, a keyed containing device isprovided. The keyed containing device includes a container and a cap.The container includes an opening and a first coupling element disposedaround the opening. The cap includes a cap body and a septum disposed inthe cap body. The cap body has a first side and a second side. The firstside of the cap body is opposite the second side of the cap body. Theseptum has a first side and a second side. The first side of the septumis opposite the second side of the septum. Further, the first and secondside of the septum faces a same direction as the first and second sideof the cap body, respectively. The first side of the cap body includes afirst side of the septum and a second coupling element adapted to couplewith the first coupling element of the container. The second side of thecap body includes the second side of the septum and a keying element.The keying element includes at least one annular ring that protrudesfrom the second side of the cap body and that is disposed concentricallyaround the septum.

In some aspects of the present disclosure, a keyed containing system isprovided that includes a container, a cap, and an electronic device. Thecontainer includes an opening and a first coupling element disposedaround the opening. The cap includes a cap body and a septum disposed inthe cap body. The cap body has a first side and a second side. The firstside of the cap body is opposite the second side of the cap body. Theseptum has a first side and a second side. The first side of the septumis opposite the second side of the septum. Further, the first and secondside of the septum faces a same direction as the first and second sideof the cap body, respectively. The first side of the cap body includes afirst side of the septum and a second coupling element adapted to couplewith the first coupling element of the container. The second side of thecap body includes the second side of the septum and a first keyingelement. The first keying element includes at least one annular ringthat protrudes from the second side of the cap body and that is disposedconcentrically around the septum. The electronic device includes asecond keying element adapted to mate with the first keying element ofthe cap, and a piercing member positioned with respect to the secondkeying element such that the piercing member pierces the septum of thecap when the second keying element of the electronic device is matedwith the first keying element of the cap.

BRIEF DESCRIPTION OF THE FIGURES

FIG. 1A illustrates a perspective view of a container device including akeyed cap and container, according to one embodiment.

FIGS. 1B and 1C illustrates a close-up perspective view and top view,respectively, of the keyed cap shown in FIG. 1A;

FIG. 2 illustrates a top view of keyed cap, according to anotherembodiment;

FIG. 3 illustrates a top view of a keyed cap, according to yet anotherembodiment;

FIGS. 4A and 4B illustrate a perspective view and top view,respectively, of keyed cap, according to yet another embodiment;

FIG. 5A illustrates a perspective view of a container device including akeyed cap and container, according to one embodiment.

FIGS. 5B and 5C illustrate a close-up perspective view and top view,respectively, of keyed cap shown in FIG. 5A; and

FIG. 6 illustrates a keyed containing system, according to oneembodiment.

DETAILED DESCRIPTION

In some aspects of the present disclosure, a keyed cap for a containeris provided. Furthermore, in some aspects, a keyed container deviceincluding a container and the keyed cap for the container is alsoprovided. Still further, in some aspects, a keyed containing systemincluding a container, keyed cap for the container, and an electronicdevice having a keying element that is adapted to mate or otherwise fitwith a specific keying element on the keyed cap. If a keyed cap has akeying element that does not correctly correspond to a specific keyingelement on an electronic device, then the keyed cap will not properlymate with the keying element on the electronic device. For example, theelectronic device may include a piercing member that pierces the keyedcap to withdraw fluid (e.g., a reagent) when the keying elements areproperly mated, but does not pierce the keyed cap when the keyingelements are not properly mated. For instance, two keying elements thatdo not match may not fit sufficiently far enough within each other topermit the piercing member to reach a septum on the cap.

The term “septum” is used broadly herein to refer generally to apartitioning element. Any of a variety of septum types may beimplemented in different embodiments. For example, a septum may beformed by, but is not limited to, membranes, fibers, a screens or mesh,valves, etc. In certain embodiments, the septum is non-permeable tofluids and able to be pierced by a piercing member (e.g., hollowedneedle) such that fluid may be extracted from the container. In someinstances, the septum is resealable when the piercing member isextracted from the septum, such that fluid cannot escape the containervia the septum after the piercing member has been removed.

The container may vary in size and shape, and may include, for example,a known reagent bottle used to hold reagents for instance. The keyed capmay be used to prevent installing a reagent in the wrong loading port,for example, which may potentially lead to cross-contamination. Assummarized above, if cross-contamination occurs, additional steps may berequired, such as flushing or otherwise decontaminating the system,which leads to wasted time and inconvenience for the user.

The keyed caps include a keying element with at least one annular ringprotrusion. The one or more annular rings provide a specificconfiguration of rings and spaces defined by the rings. The specificconfiguration created by the one or more annular rings functions as a“key” that requires a corresponding configuration on a receiving device(e.g., an electronic device) to enable the keying element on the cap tobe received. For example, the corresponding keying element on thereceiving device will be shaped and sized to properly align and receivethe one or more annular rings of the keyed cap. For instance, the keyingelement on the receiving device may include one or more annular groovesor wells that are positioned appropriately to align with the one or moreannular rings on the keyed cap. Furthermore, the keyed element on thereceiving device may include one or more annular rings that arepositioned appropriately to align with one more spaces on the keyingelement on the keyed cap that are defined by the one or more annularrings on the keyed cap.

Many annular ring configurations may be implemented in differentembodiments. Accordingly, a large number of keying configurations may beimplemented for keyed containers holding different reagents used by areceiving device to prevent accidental mixing-up of reagents within andbetween receiving devices. The receiving device may include electronicinstruments, for example, that test, analyze, process, or otherwise usereagents within the keyed container. Example electronic instruments mayinclude, but are not limited to, instruments related to hematologyanalysis. It should be appreciated that the electronic instruments mayalso include, for example, optical components that are used to performtesting, analysis, processing of the reagents, etc.

The keyed caps of the present disclosure enable a single commoncontainer to be manufactured for multiple reagents. While it is notrequired to use a common container, having a common container mayimprove manufacturability of the container and may reduce costs.

In some instances, the keyed caps may be designed with identifyingcharacteristics or features, such as having numbers, symbols, colors,etc., that are printed or otherwise included on the keyed cap to codeand identify the cap. For example, a loading area on a receiving devicemay include a matching color, number, or symbol, to serve as anadditional aid to the user.

In certain embodiments, the keyed caps are removably coupled to thecontainer. For example, the keyed caps may include threading which mateswith threading on an opening of the container. Such threadingmechanisms, or other known coupling mechanisms may be implemented toremovably couple the cap and container. In certain embodiments, thekeyed cap may be integrated within, or fixedly attached to, thecontainer. For example, the keyed cap and container may be attachedtogether with reagent inside during manufacturing. Alternatively, thekeyed cap and container may include a known locking mechanism to lockthe two components together when coupled.

In certain aspects, the annular rings on a keyed cap provide anadditional benefit of not requiring the cap to be oriented rotationally(e.g., “clocked”) to correctly mate with the receiving device. Forexample, other shapes such as polygons (e.g., hexagon, square, octagon,etc.) require the cap to be correctly oriented rotationally, or“clocked”, to enable the cap to properly mate with the receiving device.Shapes, including annular rings, not centered around the axis of the capmay also require clocking to properly align. Furthermore, irregularshapes that are not a commonly defined shape, such as a polygon, mayalso require clocking. It should be appreciated that in alternativeembodiments, other shapes requiring clocking may be implemented.

In certain aspects of the present disclosure, the container deviceincluding the keyed cap and the container is form fitted to a receivingport on the receiving device to enable the container device to insertwithin, or “plug-in” to, the port. The receiving port includes apiercing member to pierce the septum of the keyed cap when the containerdevice is inserted within the port.

Specific ports may be adapted for use with specific reagents by havingmatching the keying elements in the ports with the appropriate keyedcap. Therefore, if the receiving port and the keyed cap do not havematching keying elements, then the piercing member is prevented frompiercing the septum of the keyed cap and cross contamination is avoided.This provides an additional level of insurance that container deviceshaving specific reagents are installed in the correct ports.

The cap and container may be made from any suitable material. Examplematerials may include, but are not limited to, polymeric materials(e.g., plastic), metals, metal alloys, or combinations thereof. Theseptum may be made from any suitable material that is non-permeable tofluid but enables a piercing member to pierce the septum for fluidwithdrawal. For instance, any known septum be implemented.

To further describe the various aspects of the present disclosure,additional embodiments are described below. It should be appreciatedthat the embodiments are exemplary and that the features described maybe applicable to other embodiments.

FIG. 1A illustrates a perspective view of a container device, accordingto one embodiment. Shown in FIG. 1A, the container device 100 includes acap 101 and a container 102. FIGS. 1B and 1C illustrates a close-upperspective view and top view, respectively, of the cap 101 shown inFIG. 1A, and is described in conjunction with FIG. 1A.

Cap 101 is removably coupled to an opening of the container 102. Forexample, both the cap 101 and the container 102 may include couplingelements (not shown), such as threading, that enable the two componentsto be coupled together. In an alternative embodiment, the cap 101 andthe container 102 may be integrated or otherwise fixedly attached to oneanother.

The container 102 may be made from any suitable material, but should benon-permeable to fluid. Example materials may include, but are notlimited to, polymeric materials (e.g., plastic), metals, metal alloys,or combinations thereof.

The container 102 may include a coupling element (not shown) thatcouples to a corresponding coupling element on the cap 101. For example,the coupling element may include threading which permits the cap 101 tobe screwed on and off of the container 102. Any type of coupling elementmay be used to couple the cap 101 to the container 102. The couplingelement of the cap 101 may also include a gasket, for example, toprovide an air and/or liquid tight seal when coupled.

Cap 101 is shown including a cap body 103, septum 104, and annular ring105. Opposite sides 106,107 of cap 101 are referred to herein forreference purposes. Side 106 (e.g., the top side of cap 101) faces awayfrom the container when cap 101 is coupled to container 102. Similarly,side 107 (e.g., the bottom side of cap 101) faces toward the containerwhen cap 101 is coupled to the container.

The septum 104 is disposed in the cap body 103 with one side of septum104 on side 106, and the opposite side of septum 104 on side 107. Forexample, side 107 of septum 104 and cap body 103 face the container 102when coupled to the container 102. Similarly, side 106 of septum 104 andcap body 103 face away from container 102 when coupled to the container102.

In the embodiment shown, the septum is non-permeable to fluids, but ispermeable to a piercing member of a device that withdraws fluid from thecontainer—e.g., via an inner lumen of the piercing member. It should beappreciated that in other embodiments, the size and/or shape of theseptum may vary.

Cap 101 includes annular ring 105 which protrudes from side 106 of capbody 103. In the embodiment shown, the septum 104 is disposed in thecenter of cap body 103 with the annular ring 105 disposed concentricallyaround the septum 104. The annular ring 105 defines a space 108 betweenthe annular ring 105 and the septum 104, and a space 109 between annularring 105 and the outer perimeter cap body 103.

The annular ring 105 may vary in thickness in different embodiments.Furthermore, the spaces 108 and 109 may also vary in differentembodiments. For example, as shown in FIG. 1C, the thickness of theannular ring 105 is represented as t1, with spaces 108 and 109 havingwidths d1 and d2, respectively.

FIG. 2 illustrates cap 201 including a cap body 203 similar to shown inFIGS. 1A-1C, except that the annular ring 205 and spaces 5 208 and 209differ from the from the annular ring 105 and spaces 108 and 109 shownin the embodiment shown in FIGS. 1A-1C. Annular ring 205 in FIG. 2 has athickness, which represents a thickness greater than the thickness shownfor annular ring 105 in FIGS. 1A-1C. Furthermore, spaces 208 and 209have different widths than the widths 108 and 109, respectively. Thesethicknesses and widths referred to herein are measured from the innerradius to the outer radius of the corresponding ring or space—e.g., asbest seen in the top-view. For instance, the width of space 208 issmaller than the width 108. It is also noted that the radial positioningof spaces may also vary independently of the widths. The term “radialpositioning” is used broadly herein to represent the general distancefrom the center of the cap to the center of the annular ring (e.g., 205)or spaces (e.g., 208 and 209) defined by the annular ring.

FIG. 3 illustrates a top view of a cap according to another embodiment.Cap 301 includes a cap body 303, septum 304, and annular ring 305. Oneside of septum 304 is exposed and faces towards container 102 when cap301 is coupled to container 102. The opposite side of septum 304 isexposed and faces away from container 102 when cap 301 is coupled tocontainer 102—e.g., the side shown in the top view illustration.

Annular ring 305 protrudes from the side of cap body 303 that faces awayfrom the container 102 when the cap 301 is coupled to the container102—e.g., the side shown in the top view illustration.

Annular ring 305 is disposed concentrically around septum 304 at theouter perimeter of cap body 303, defining space 308 between annular ring305 and septum 304.

It should be appreciated that the size of the keyed cap, and componentswithin the keyed cap (e.g., annular rings, spaces defined by the annularrings, septum, etc.) may vary in different embodiments. The size of thekeyed cap and components thereof may vary but should enable propermating with the appropriately sized keying element of the receivingdevice. In certain embodiments, the size of the cap may range from, butis not limited to, three inches or less, such as two inches or less, andincluding one inch or less. In certain embodiments, the size of theannular rings may range from, but are not limited to, two centimeters orless, such as one centimeter or less, and including half a centimeter orless. In certain embodiments, the thickness of the annular rings mayrange depending on the size of the keyed cap being used. These examplesizes are provided for exemplary purposes and should not be construed aslimiting.

In certain embodiments, the cap may include more than one annular ring.For example, FIGS. 4A and 4B illustrate a perspective view and top view,respectively, of cap 401. Side 406 of cap 401 faces away from thecontainer 102 when coupled to the container 102, and side 407 facestoward the container 102 when coupled to the container 102. Cap 401includes a cap body 403, septum 404 exposed on both sides 406 and 407,and annular rings 405 a,405 b protruding from side 406 of cap body 403.

Annular ring 405 a is disposed concentrically around septum 404 definingspace 408 between annular ring 405 a and septum 404. Annular ring 405 bis disposed concentrically around both annular ring 405 a and septum404. In the embodiment shown, annular ring 405 b is disposed at theouter perimeter of cap body 403 and defines a space 409 between annularring 405 a and annular ring 405 b.

FIG. 5A illustrates a perspective view of a container device, accordingto one embodiment. Shown in FIG. 5A, the container device 500 includes acap 501 and a container 502. FIGS. 5B and 5C illustrates a close-upperspective view and top view, respectively, of the cap 501 shown inFIG. 5A, and is described in conjunction with FIG. 5A.

Side 506 of cap 501 faces away from the container 102 when coupled tothe container 102, and side 507 faces toward the container 102 whencoupled to the container 102. Cap 501 includes a cap body 503, septum504 exposed on both sides 506 and 507, and annular rings 505 a,505 bprotruding from side 506 of cap body 503.

Annular rings 505 a,505 b protrude from the side of cap body 503 thatfaces away from the container 102 when the cap 501 is coupled to thecontainer 102—e.g., the side shown in the top view illustration.

Annular ring 505 a is disposed concentrically around septum 504 definingspace 508 between annular ring 505 a and septum 504. Annular ring 505 bis disposed concentrically around both annular ring 505 a and septum504, defining space 509 between annular ring 505 a and annular ring 505b. Annular ring 505 b also defines space 510 between annular ring 505 band the outer perimeter of cap body 503.

It should be appreciated that the embodiments shown are exemplary, andthat other embodiments may include more than two annular rings. Itshould also be appreciated that the height of each annular ring may varyin different embodiments. In certain embodiments, each annular ring hasthe same height. In other embodiments, two or more annular rings havedifferent heights. For example, in the embodiment shown in FIG. 4A,annular ring 405 a is greater in height than annular ring 405 b. Inother embodiments, such as the embodiment shown in FIG. 5B, the annularrings have the same height.

It should be appreciated that depth of each space defined by the annularrings may vary in different embodiments. The “depth” of each space isused herein to refer generally to the distance in the space from the capbody to the distal height of the annular ring. It is also understoodthat some spaces may be surrounded by two annular rings of differentheights. In such case, the “depth” of the space may be defined based onthe height of one or both annular rings—e.g., the depth of the space maybe refer generally to the distance from the cap body to the distalheight of either annular ring, or a combination of the two annular ringssuch as the middle of the two annular rings, etc. In some instances, thecap body within two spaces may differ in height from one another.

In certain embodiments, each space defined by the annular rings has thesame depth. In other embodiments, two or more spaces have differentdepths. It should be appreciated that the base surfaces of a two spacesmay be at different height levels, or alternatively may be at the sameheight level.

The height of the septum may also vary in different embodiments. Forexample, in the embodiment shown in FIG. 4A, the cap body 403 includes araised center portion where the septum is disposed, and the septum 104is raised to the same height as annular ring 405 b. In the embodimentshown in FIG. 5B, the septum 104 is lower than the height of either ofthe annular rings 505 a,505 b. For instance, the height of the septummay be disposed at the height level where the annular rings 505 a,505 bmeet the top surface of the cap body 503.

It is appreciated that the following parameters may vary in differentembodiments: thickness and heights of the annular rings; the widths anddepths of the spaces defined by the annular rings; and the radialpositioning of the annular rings and spaces defined by the annularrings.

It is also appreciated that in certain embodiment, the first annularring may be at a different height than the second annular ring, andfurther may be abutting the second annular ring. In such case, no spaceis formed between the two annular rings, however, the keying element onthe receiving device may still include matching protrusions atcorresponding heights to enable a “keyed” fit. It should also beappreciated that the first annular ring and the second annular ring maybe made from two separate pieces or from a single piece of materialmolded or shaped accordingly.

FIG. 6 illustrates a container system, according to one embodiment. Thecontainer system 600 includes a container 102 having cap 501 coupledthereto. For the embodiment shown, cap 501 is the same cap 501 as shownin FIG. 5A-5C. The container may include fluids, such as reagents forexample. Container system also includes an electronic device 600 thathas two ports 601,603. Port 601 includes a keying element 602 to matewith a specific annular ring configuration of a corresponding cap inwhich it is “keyed” to. Similarly, port 603 includes a keying element604 that mates with a different specific annular ring configurationcorresponding to a different cap.

Keying element 604 is sized and shaped to mate with cap 501. The annularrings and spaces of cap 501 form a keying element that is shaped andsized to mate with keying element 604. For example, keying element 604includes a first annular ring 609 which aligns within space 508 of cap501; a second annular ring 607 which aligns within space 509 of cap 501;and a portion of surface 605 that aligns with space 510 of cap 50; and acentral piercing member 611 which pierces septum 504 of cap 501 when cap501 is mated with the keying element 604. Similarly, keying element 604includes a space 608 that aligns with annular ring 505 a of cap 501; andspace 606 that aligns with annular ring 505 b of cap 501. Accordingly,when the containing device including the container 102 and cap 501 isbrought towards port 603, the keying element 604 aligns with theprotrusions and spaces of cap 501, enabling the cap 501 to fit withinthe keying element 604 and pierce septum 504 with the central piercingmember 611.

It is appreciated that the piercing member 611 is positioned at theproper height to permit the piercing member to pierce the septum. Thus,for example, a keyed cap that does not match the keying element of thereceiving element is not permitted to insert far enough to allow thepiercing member to pierce the septum.

Keying element 602 of port 601 is sized and shaped to mate withdifferent cap than 501. For example, keying element 602 is sized andshaped to mate with cap 301 shown in FIG. 3. For example, keying element602 includes a central piercing member 616 which pierces septum 304 ofcap 301; and a first annular ring 614 which aligns within space 308 ofcap 301. Similarly, keying element 604 includes a space 613 that alignswith annular ring 305 of cap 301.

In FIG. 6, cap 501 includes annular rings 505 a,505 b and spaces508,509,510 that form a keying element of cap 501. Keying element of cap501 does not properly mate with the keying element 602 of port 601because the annular rings 505 a,505 b and spaces 508,509,510 do notproperly align with the annular ring 614 and spaces 613,615 of keyedelement 602. For example, annular rings 505 a,505 b will contact keyingelement 602 but will not properly align and mate with keying element602. Because of the improper alignment, the cap 501 is prevented fromsufficient insertion to enable piercing member 616 from piercing septum504. This provides a safety mechanism to ensure that the container isnot inserted within an incorrect port, risking cross-contamination ofreagents. If cross-contamination occurs, additional steps may berequired, such as flushing or otherwise decontaminating the system,which causes wasted time and reagent.

Additional Example Embodiments

In some aspects of the present disclosure, a keyed cap is provided. Thecap includes a cap body and a septum disposed in the cap body. The capbody has a first side and a second side. The first side of the cap bodyis opposite the second side of the cap body. The septum has a first sideand a second side. The first side of the septum is opposite the secondside of the septum. Further, the first and second side of the septumfaces a same direction as the first and second side of the cap body,respectively. The first side of the cap body includes a first side ofthe septum and a coupling element for coupling to a container. Thesecond side of the cap body includes the second side of the septum and akeying element. The keying element includes at least one annular ringthat protrudes from the second side of the cap body and that is disposedconcentrically around the septum.

In certain embodiments, the keying element comprises a first annularring disposed between the septum and an outer perimeter of the cap body.

In certain embodiments, the keying element comprises a second annularring. In some instances, the second annular ring is disposed between theseptum and an outer perimeter of the cap body. In some instances, thekeying element comprises a second annular ring disposed at an outerperimeter of the cap body. In some instances, the first annular ring andthe second annular ring have different heights. In some instances, thefirst annular ring and the second annular ring have differentthicknesses.

In certain embodiments, the keying element comprises a third annularring. In some instances, the third annular ring is disposed between theseptum and the outer perimeter of the cap body. In some instances, eachof the first, second, and third annular rings have different heights. Insome instances, at least two of the first, second, and third annularrings have equal heights. In some instances, each of the first, second,and third annular rings have different thicknesses. In some instances,at least two of the first, second, and third annular rings have equalthicknesses.

In some aspects of the present disclosure, a keyed containing device isprovided. The keyed containing device includes a container and a cap.The container includes an opening and a first coupling element disposedaround the opening. The cap includes a cap body and a septum disposed inthe cap body. The cap body has a first side and a second side. The firstside of the cap body is opposite the second side of the cap body. Theseptum has a first side and a second side. The first side of the septumis opposite the second side of the septum. Further, the first and secondside of the septum faces a same direction as the first and second sideof the cap body, respectively. The first side of the cap body includes afirst side of the septum and a second coupling element adapted to couplewith the first coupling element of the container. The second side of thecap body includes the second side of the septum and a keying element.The keying element includes at least one annular ring that protrudesfrom the second side of the cap body and that is disposed concentricallyaround the septum.

In certain embodiments, the keying element comprises a first annularring disposed between the septum and an outer perimeter of the cap body.

In certain embodiments, the keying element comprises a second annularring. In some instances, the second annular ring is disposed between theseptum and an outer perimeter of the cap body. In some instances, thekeying element comprises a second annular ring disposed at an outerperimeter of the cap body. In some instances, the first annular ring andthe second annular ring have different heights. In some instances, thefirst annular ring and the second annular ring have differentthicknesses.

In certain embodiments, the keying element comprises a third annularring. In some instances, the third annular ring is disposed between theseptum and the outer perimeter of the cap body. In some instances, eachof the first, second, and third annular rings have different heights. Insome instances, at least two of the first, second, and third annularrings have equal heights. In some instances, each of the first, second,and third annular rings have different thicknesses. In some instances,at least two of the first, second, and third annular rings have equalthicknesses.

In some aspects of the present disclosure, a keyed containing system isprovided that includes a container, a cap, and an electronic device. Thecontainer includes an opening and a first coupling element disposedaround the opening. The cap includes a cap body and a septum disposed inthe cap body. The cap body has a first side and a second side. The firstside of the cap body is opposite the second side of the cap body. Theseptum has a first side and a second side. The first side of the septumis opposite the second side of the septum. Further, the first and secondside of the septum faces a same direction as the first and second sideof the cap body, respectively. The first side of the cap body includes afirst side of the septum and a second coupling element adapted to couplewith the first coupling element of the container. The second side of thecap body includes the second side of the septum and a first keyingelement. The first keying element includes at least one annular ringthat protrudes from the second side of the cap body and that is disposedconcentrically around the septum. The electronic device includes asecond keying element adapted to mate with the first keying element ofthe cap, and a piercing member positioned with respect to the secondkeying element such that the piercing member pierces the septum of thecap when the second keying element of the electronic device is matedwith the first keying element of the cap.

In certain embodiments, the second keying element includes at least oneannular ring positioned to align with spaces defined by at least oneannular ring of the first keying element.

In certain embodiments, the second keying element includes at least onespace defined by an annular ring, the at least one space of the secondkeying element positioned to align with at least one annular ring of thefirst keying element.

In certain embodiments, the first keying element comprises a firstannular ring disposed between the septum and an outer perimeter of thecap body.

In certain embodiments, the first keying element comprises a secondannular ring. In some instances, the second annular ring of the firstkeying element is disposed between the septum and an outer perimeter ofthe cap body. In some instances, the first keying element comprises asecond annular ring disposed at an outer perimeter of the cap body. Insome instances, the first annular ring and the second annular ring ofthe first keying element have different heights. In some instances, thefirst annular ring and the second annular ring of the first keyingelement have different thicknesses.

In certain embodiments, the first keying element comprises a thirdannular ring. In some instances, the third annular ring of the firstkeying element is disposed between the septum and the outer perimeter ofthe cap body. In some instances, each of the first, second, and thirdannular rings of the first keying element have different heights. Insome instances, at least two of the first, second, and third annularrings of the first keying element have equal heights. In some instances,each of the first, second, and third annular rings of the first keyingelement have different thicknesses. In some instances, at least two ofthe first, second, and third annular rings of the first keying elementhave equal thicknesses.

In some aspects of the present disclosure, an electronic device isprovided that includes a keying element adapted to mate with anotherkeying element of a keyed cap according to the present disclosure. Theelectronic device includes a piercing member positioned with respect tothe keying element of the electronic device, such that the piercingmember pierces the septum of the keyed cap when the keying element ofthe electronic device is mated with the first keying element of the cap.

In certain embodiments, the keying element of the electronic deviceincludes at least one annular ring positioned to align with spacesdefined by at least one annular ring of the keying element of the keyedcap.

In certain embodiments, the keying element of the electronic deviceincludes at least one space defined by an annular ring, the at least onespace of the keying element of the electronic device is positioned toalign with at least one annular ring of the keying element of the keyedcap.

Although the foregoing embodiments have been described in some detail byway of illustration and example for purposes of clarity ofunderstanding, it is readily apparent to those of ordinary skill in theart in light of the teachings of the present disclosure that certainchanges and modifications may be made thereto without departing from thespirit or scope of the appended claims. It is also to be understood thatthe terminology used herein is for the purpose of describing particularembodiments only, and is not intended to be limiting.

Where a range of values is provided, it is understood that eachintervening value, to the tenth of the unit of the lower limit unlessthe context clearly dictates otherwise, between the upper and lowerlimit of that range and any other stated or intervening value in thatstated range, is encompassed within the invention. The upper and lowerlimits of these smaller ranges may independently be included in thesmaller ranges and are also encompassed within the invention, subject toany specifically excluded limit in the stated range. Where the statedrange includes one or both of the limits, ranges excluding either orboth of those included limits are also included in the invention.

All publications and patents cited in this specification are hereinincorporated by reference as if each individual publication or patentwere specifically and individually indicated to be incorporated byreference and are incorporated herein by reference to disclose anddescribe the methods and/or materials in connection with which thepublications are cited. The citation of any publication is for itsdisclosure prior to the filing date and should not be construed as anadmission that the present invention is not entitled to antedate suchpublication by virtue of prior invention. Further, the dates ofpublication provided may be different from the actual publication dateswhich may need to be independently confirmed.

It is noted that, as used herein and in the appended claims, thesingular forms “a”, “an”, and “the” include plural referents unless thecontext clearly dictates otherwise. It is further noted that the claimsmay be drafted to exclude any optional element. As such, this statementis intended to serve as antecedent basis for use of such exclusiveterminology as “solely,” “only” and the like in connection with therecitation of claim elements, or use of a “negative” limitation.

As will be apparent to those of skill in the art upon reading thisdisclosure, each of the individual embodiments described and illustratedherein has discrete components and features which may be readilyseparated from or combined with the features of any of the other severalembodiments without departing from the scope or spirit of the presentinvention. Any recited method can be carried out in the order of eventsrecited or in any other order which is logically possible.

Accordingly, the preceding merely illustrates the principles of theinvention. It will be appreciated that those skilled in the art will beable to devise various arrangements which, although not explicitlydescribed or shown herein, embody the principles of the invention andare included within its spirit and scope. Furthermore, all examples andconditional language recited herein are principally intended to aid thereader in understanding the principles of the invention and the conceptscontributed by the inventors to furthering the art, and are to beconstrued as being without limitation to such specifically recitedexamples and conditions. Moreover, all statements herein recitingprinciples, aspects, and embodiments of the invention as well asspecific examples thereof, are intended to encompass both structural andfunctional equivalents thereof. Additionally, it is intended that suchequivalents include both currently known equivalents and equivalentsdeveloped in the future, i.e., any elements developed that perform thesame function, regardless of structure. The scope of the presentinvention, therefore, is not intended to be limited to the exemplaryembodiments shown and described herein.

The invention claimed is:
 1. A keyed containing system, comprising: acontainer, the container comprising: an opening; and a first couplingelement disposed around the opening; and a cap, the cap comprising: acap body comprising a first side comprising a first surface and a secondside comprising a second surface, wherein the first side of the cap bodyis opposite the second side of the cap body and the first surface isopposite the second surface; and a septum disposed in the cap body,wherein the septum has a first material and has a first side and asecond side, wherein the first side of the septum is opposite the secondside of the septum, and wherein the first and second side of the septumface a same direction as the first and second side of the cap body,respectively; wherein a first side of the cap body comprises: the firstside of the septum; and a second coupling element adapted to couple withthe first coupling element of the container; wherein the second side ofthe cap body comprises: the second side of the septum; and a keyingelement, wherein the keying element comprises at least one annular ringprotruding from the second side of the cap body and defining on thesecond surface a first space between the annular ring and the septum,and a second space between the annular ring and an outer perimeter ofthe cap body, wherein the at least one annular ring is disposedconcentrically around the septum, and wherein the at least one annularring is comprises of a second material that is different from the firstmaterial; and a device comprising a keying element adapted to mate withthe keying element of the cap.
 2. The keyed containing device of claim1, wherein the keying element comprises a first annular ring disposedbetween the septum and an outer perimeter of the cap body.
 3. The keyedcontaining device of claim 1, wherein the keying element comprises asecond annular ring.
 4. The keyed containing device of claim 3, whereinthe second annular ring is disposed between the septum and an outerperimeter of the cap body.
 5. The keyed containing device of claim 3,wherein the keying element comprises a second annular ring disposed atan outer perimeter of the cap body.
 6. The keyed containing device ofclaim 3, wherein the first annular ring and the second annular ring havedifferent heights.
 7. The keyed containing device of claim 3, whereinthe first annular ring and the second annular ring have differentthicknesses.
 8. The keyed containing device of claim 3, wherein thekeying element comprises a third annular ring.
 9. The keyed containingdevice of claim 8, wherein the third annular ring is disposed betweenthe septum and the outer perimeter of the cap body.
 10. The keyedcontaining device of claim 8, wherein each of the first, second, andthird annular rings have different heights.
 11. The keyed containingdevice of claim 8, wherein at least two of the first, second, and thirdannular rings have equal heights.
 12. The keyed containing device ofclaim 8, wherein each of the first, second, and third annular rings havedifferent thicknesses.
 13. The keyed containing device of claim 8,wherein at least two of the first, second, and third annular rings haveequal thicknesses.
 14. The keyed containing device according to claim 1,wherein an inner diameter of the annular ring is greater than an outerdiameter of the spectrum.
 15. A keyed containing system, comprising: acontainer, the container comprising: an opening; and a first couplingelement disposed around the opening; and a cap, the cap comprising: acap body having a first side and a second side, wherein the first sideof the cap body is opposite the second side of the cap body; and aseptum disposed in the cap body, wherein the septum has a first side anda second side, wherein the first side of the septum is opposite thesecond side of the septum, and wherein the first and second side of theseptum faces a same direction as the first and second side of the capbody, respectively; wherein a first side of the cap body comprises: thefirst side of the septum; and a second coupling element adapted tocouple with the first coupling element of the container; wherein thesecond side of the cap body comprises: the second side of the septum;and a first keying element, wherein the first keying element comprisesat least one annular ring protruding from the second side of the capbody, wherein the at least one annular ring is disposed concentricallyaround the septum; and an electronic device, the electronic devicecomprising: a second keying element adapted to mate with the firstkeying element of the cap; and a piercing member positioned with respectto the second keying element such that the piercing member pierces theseptum of the cap when the second keying element of the electronicdevice is mated with the first keying element of the cap.
 16. The keyedcontaining system of claim 15, wherein the second keying elementincludes at least one annular ring positioned to align with spacesdefined by at least one annular ring of the first keying element. 17.The keyed containing system of claim 15, wherein the second keyingelement includes at least one space defined by an annular ring, the atleast one space of the second keying element positioned to align with atleast one annular ring of the first keying element.
 18. The keyedcontaining system of claim 15, wherein the first keying elementcomprises a first annular ring disposed between the septum and an outerperimeter of the cap body.
 19. The keyed containing system of claim 15,wherein the first keying element comprises a second annular ring. 20.The keyed containing system of claim 19, wherein the second annular ringof the first keying element is disposed between the septum and an outerperimeter of the cap body.
 21. The keyed containing system of claim 19,wherein the first keying element comprises a second annular ringdisposed at an outer perimeter of the cap body.
 22. The keyed containingsystem of claim 19, wherein the first annular ring and the secondannular ring of the first keying element have different heights.
 23. Thekeyed containing system of claim 19, wherein the first annular ring andthe second annular ring of the first keying element have differentthicknesses.
 24. The keyed containing system of claim 19, wherein thefirst keying element comprises a third annular ring.
 25. The keyedcontaining system of claim 24, wherein the third annular ring of thefirst keying element is disposed between the septum and the outerperimeter of the cap body.
 26. The keyed containing system of claim 24,wherein each of the first, second, and third annular rings of the firstkeying element have different heights.
 27. The keyed containing systemof claim 24, wherein at least two of the first, second, and thirdannular rings of the first keying element have equal heights.
 28. Thekeyed containing system of claim 24, wherein each of the first, second,and third annular rings of the first keying element have differentthicknesses.
 29. The keyed containing system of claim 24, wherein atleast two of the first, second, and third annular rings of the firstkeying element have equal thicknesses.
 30. The keyed containing systemof claim 15, wherein the first side of the cap body comprises a firstsurface, wherein the second side of the cap body comprises a secondsurface opposite the first surface, and wherein the at least one annularring of the first keying element protrudes orthogonally from the secondsurface.
 31. The keyed containing system of claim 15, wherein the firstside of the cap body comprises a first surface, wherein the second sideof the cap body comprises a second surface opposite the first surface,and wherein the at least one annular ring of the first keying elementdefines on the second surface a first space between the annular ring andthe septum, and a second space between the annular ring and an outerperimeter of the cap body.